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  • 2nd Alzheimer’s drug approved by FDA: donanemab (Kisunla) by Eli Lilly

Jul 3, 2024

2nd Alzheimer’s drug approved by FDA: donanemab (Kisunla) by Eli Lilly

Bay Area Times
Bay Area Times

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Top stories today:

  1. 2nd Alzheimer’s drug approved by FDA: donanemab (Kisunla) by Lilly
  2. Figma disables Make Design feature after it was found copying Apple
  3. Runway AI in talks to raise $450M at $4B valuation
  4. Tesla stock +10% after deliveries fall less than expected
  5. Exits for Europe’s VC-backed fintechs continue to decelerate

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0. Data and calendar

All values as of 6 AM ET / 3 AM PT, other than S&P500 and NASDAQ close (4 PM ET / 1 PM PT).

All times are ET.

1. 2nd Alzheimer’s drug approved by FDA: donanemab (Kisunla) by Eli Lilly

22%-36% slowdown of clinical decline was observed in donanemab’s Phase 3 clinical trial:

Sims, et al. Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA.

  • $13K for a 6-month course, $32K for 12 months, and $49K for 18 months.

  • Similar efficacy and pricing vs. lecanemab, the 1st approved Alzheimer’s drug from Eisai.

    • Donanemab requires shots every month, rather than every 2 weeks.

  • Lilly stock -1%.

  • Alzheimer’s drug market expected at $13B/year by 2030, from $0.25B in 2024.

2. Figma disables Make Design feature after it was found copying Apple’s designs

X: Figma CEO Dylan Field.

  • Figma says that they did not train their own models.

    • OpenAI’s GPT-4o and Amazon’s Titan Image Generator G1 are used instead.

  • “Soon”: when Make Designs will be re-enabled.

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4. Runway AI in talks to raise $450M at $4B valuation

It would make the text-to-video AI firm the #10 most valuable generative AI startup:

Generative AI Unicorns Database.

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