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Alphafold 3 launched by Google Deepmind, who hopes to build “$100B’s+ business”

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Top stories today:

  1. Alphafold 3 launched by Google Deepmind
  2. Mistral nears raise of $600M at $6B valuation
  3. OpenAI shares “Model Spec,” doc on how they want AI models to behave
  4. iPhone shipments in China +12% YoY to 3.75M units in Mar.
  5. China’s exports +1.5% YoY in Mar., imports +8.4%, after drops in Feb.

0. Data and calendar

All values as of 6 AM ET / 3 AM PT, other than S&P500 and NASDAQ close (4 PM ET / 1 PM PT).

All times are ET.

1. Alphafold 3 launched by Google Deepmind, who hopes to build “$100B’s+ business”

Deepmind CEO Demis Hassabis expects drugs in the clinic “in the next couple of years”

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3. Mistral nears raise of $600M at $6B valuation

Making it the #6 most valuable generative AI startup:

  • Likely led by existing investors General Catalyst and Lightspeed Venture Partners.

  • Unclear how they can compete with Meta’s Llama 3 on open source AI and with OpenAI, Anthropic, and Google on closed source AI, given these companies are literally investing $10B’s.

    • A breakthrough in AI algorithms (e.g. Transformers 2.0) is likely required.

4. OpenAI shares “Model Spec,” doc specifying how they want AI models to behave

5. iPhone shipments in China +12% YoY to 3.75M units in Mar., from -37% in Feb., after discounts

6. China’s exports +1.5% YoY in Mar., imports +8.4%, after drops in Feb.

7. U.S. expected to manufacture 28% of <10nm chips by 2032, from 0% today

8. Interesting videos, posts, and memes

9. Other headlines


  • xAI nears close of $6B at $18B pre-money valuation round.

  • Microsoft Copilot introduces new AI features, including autocomplete.

  • Stack Overflow banning users to deleted answers ahead of OpenAI partnership.

  • Atlan, AI data catalog, raises $105M at $750M valuation.

  • Datology AI raises $46M for AI model training data.

  • Microsoft to invest $3B+ in AI infrastructure in Wisconsin.

  • MindStudio: How to Build An AI Agency.*

  • guidde: magically create video documentation with AI.*


Tech earnings


  • Kinde: customer identity and access management in a few lines of code.*


Tech & law

  • AI model China export curb likely to be introduced by U.S.

  • Tesla probed for potentially misleading investors, consumers over self-driving.


  • Neuralink posts update on 1st patient, who already plays videogames.

  • Fountain Life launches $2995/year CORE membership for longevity.

  • Alzheimer’s and aging as a target for prevention, treatment.


  • Trump pledges support crypto, “I'm fine with it, I wanna make sure it's good.”

  • Memecoin index launched by VanEck.

  • Binance accused of firing investigator that identified suspicious trading.

  • Nigeria rejects Binance’s allegation of bribery.

U.S. politics

  • House rejects MTG’s attempt to remove Speaker Johnson by 359-43.


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