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Top stories today:
- Elon’s xAI co-founder Jimmy Ba exits as researcher departures mount
- Isomorphic Labs unveils IsoDDE, claiming leap beyond AlphaFold 3
- Moderna flu vaccine blocked as FDA declines review of mRNA shot
- Sam Bankman-Fried seeks new trial, citing new witnesses in FTX fraud
- Runway raises $315M Series E round at $5.3B valuation
- Mistral ARR tops $400M, targets $1B by 2026
- ChatGPT Deep Research upgraded with GPT-5.2, site-focused reports
0. Data and calendar
1. Elon’s xAI co-founder Jimmy Ba exits as researcher departures mount
Ba becomes the 6th founding member to leave xAI
Likely connected to vesting of xAI stock given its sale to SpaceX.
Mon.: Tony Wu became the 5th founder to exit the 12-person team that launched xAI in 2023.
6+ xAI researchers have left in recent weeks, per sources and social posts.
Anthropic is the only major AI lab that has retained all its (7) co-founders.
Tue.: Elon Musk held a staff call to discuss changes in technical leadership.
Leadership overpromised progress to Musk as xAI raced to catch OpenAI and Anthropic, some employees reportedly said.
2. Isomorphic Labs unveils IsoDDE, claiming leap beyond AlphaFold 3 in drug design
On the Runs N’ Poses benchmark, IsoDDE more than doubles AlphaFold 3’s accuracy on the hardest cases:
IsoDDE outperformed AlphaFold 3 by 2.3× and Boltz-2 by ~20× on high-fidelity antibody–antigen predictions
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Full-stack LLM integration
Production-ready implementation
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*Disclaimer: We have equity in Athyna.
4. Moderna flu vaccine blocked as FDA declines review of mRNA shot
