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Novo Nordisk moves to secure rapid FDA approval for 7.2mg Wegovy dose

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Top stories today:

  1. Novo Nordisk moves to secure rapid approval for 7.2mg Wegovy dose
  2. OpenAI data-center partners said to near $100B debt, eye $38B more
  3. Project Prometheus, Jeff Bezos’ venture, acquires General Agents
  4. Upbit halts deposits, withdrawals after ~$30M unauthorized transfer
  5. Alibaba unveils Quark S1, G1 AI glasses with translucent displays
  6. Trump pushes “reverse migration” plan following D.C. attack

0. Data and calendar

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No major events today.

Listen to our AI-generated podcast summarizing today’s newsletter (beware of hallucinations):

1. Novo Nordisk moves to secure rapid FDA approval for 7.2mg Wegovy dose

  • The 1,407-person trial showed the 7.2mg dose delivering 20.7% weight loss over 72 weeks.

  • Under the FDA’s new Commissioner’s National Priority Voucher program, the application is being fast-tracked.

  • The 7.2mg formulation is already under review in the UK, EU, and other regions, with an EU decision expected in Q1 2026.

  • Late 2025: a U.S. decision is expected.

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3. OpenAI data-center partners said to near $100B debt, eye $38B in new loans

  • SoftBank, Oracle, and CoreWeave have reportedly borrowed at least $30B to invest in OpenAI or to help set up its data centers.

  • Blue Owl Capital and infra firms including Crusoe rely on OpenAI-linked deals to support ~$28B in loans.

  • OpenAI plans to raise debt for these contracts, its execs said, but the financial load has so far fallen on partners and their lenders.

  • The commitments far exceed OpenAI’s expected ARR of ~$20B this year.

4. Project Prometheus, Jeff Bezos’ new venture, acquires agentic AI startup General Agents

General Agents co-founder Sherjil Ozair has updated his X bio to reflect the transition:

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