Tirzepatide for weight loss (Zepbound) approved by FDA, has higher efficacy vs. Ozempic

Top stories today:
- Tirzepatide for weight loss (Zepbound) approved by FDA
- Humane AI Pin to be launched today, likely $699 + $24/mo
- GitHub announces Copilot Enterprise for $39/mo, out in Feb.
- Israel: U.S. strikes Syria, negotiating 3-day pause for 15 hostages
- NASA Plus, free streaming service, launches
- U.S. population to peak at 370M in 2080: Census projection
0. Data and calendar

All values as of 6 AM ET / 3 AM PT, other than S&P500 close (4 PM ET / 1 PM PT).

All times are ET.
1. Tirzepatide for weight loss (Zepbound) approved by FDA, has higher efficacy vs. Ozempic

Its U.S. list price is $1,060, around its main competitors
End-of-year:Β expected launch. - FDA
Restaurants are betting these drugs will increase sales of healthier foods.
2. Humane AI Pin to be launched today, likely $699 + $24/mo
$24/mo includes a phone number and cell data on T-Mobile.
Uses OpenAI and Microsoft models.
Comes with 2 βbattery boostersβ which can be swapped in.
Used by the Bay Area Times team.
One-click install,Β as a Chrome extension.
5.0 stars on the Chrome Web Store.
#1 product of the day (Product Hunt)
*Sponsored.
4. GitHub announces Copilot for Enterprise for $39/mo, out in Feb.
More expensive than $19/moΒ for businesses and $10/mo for individuals.
Enterprise's codebase is connected to Copilot.
Copilot now has positive gross margins, according to GitHub CEO Thomas Dohmke.
Copilot was losing $20/mo/user at the start of 2023, according to a WSJ report.
GitHub Copilot ChatΒ out in Dec. 2023.
Watch the GitHub Universe 2023 keynote here
5. Israel: U.S. strikes Syria facility, negotiating 3-day pause for 15 hostages
U.S. strikes Iran-linked weapons storage facility in Syria.
3-day pause being negotiated in exchange for 15 hostages.
Blinken: post-war Gaza should be run by Palestinian Authority.
130 tunnel entrances destroyed by IDF.
Houthis shoot down U.S. drone in Yemen.
White House condemns Rep. Tlaib for βfrom the river to the sea.β
6. NASA Plus, free streaming service, launches
7. U.S. population to peak at 370M in 2080: Census projection
Our view: population growth helps curb the CCP threat
Current trends will decrease China's population advantage vs. the U.S. from 4x to 2x, as China's population is expected to decrease from 1.4B to 800M over the century.
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8. Interesting videos, posts, and memes
9. Other headlines
AI
ChatGPT, OpenAI's APIs experience outage, cyber-attack risk.
Anthropic to be one of 1st to use Google's Cloud TPU v5e chips.
Google's Search Generative Experience expands to 120 countries, in beta.
1B Windows 10 users to have Copilot soon.
Samsung Galaxy AI will translate audio, text in real time.
DreamWorks co-founder: AI to cut cost of animated films by 90%.
Hypertype is the best AI that answers emails using your company data.*
*Sponsored.
Tech earnings
SoftBank's revenue +1% YoY to $21.4B in Q2-Q3.
Disney's revenue +5% to $21.2B in Q3; streaming still losing money.
Take-Two (GTA maker)'s bookings -4% to $1.44B.
Lyft's revenue +10% to $1.16B, vs. Uber's +11%.
Twilio's revenue +5% to $1.03B.
Arm's revenue +28% to $806M, as P/S remains at 17.
Roblox's bookings +20% to $839.5M.
Instacart's revenue +14% to $764M.
NYT's revenue +9% to $598M, 10.2M subscribers.
Hubspot's revenue +26% to $558M.
Tech
Quantum startup Photonic raises $100M from Microsoft, others.
Disney+, Hulu to launch beta of unified app next month.
GM recalling all 950 Cruise autonomous cars for software update.
One Medical reduced from $199/yr to $99/yr for Prime members.
Signal testing usernames, to avoid phone requirement.
Steve Wozniak suffers possible stroke in Mexico.
Snap lays off 20 product managers.
Sidebar is a leadership program that accelerates your career.*
Sportradar: NBA player tracking measures usage like never before.*
*Sponsored.
Tech & law
SpaceX wins order blocking suit claiming it did not hire foreigners.
India, Twitter, other platforms colluded to censor.
Google offered Epic $147M to launch Fortnite on Play Store.
Zuckerberg rejected initiatives to curb teen use: court filings.
Apple suffers setback in $14B EU tax bill.
Biotech
L-Nutra raises $47M for longevity nutrition programs.
Rejuvenation Startup Summit 2024 announces 1st speakers.
FDA approves Recor's high blood pressure device.
Insilico, SRW partner to launch AI-based nutraceuticals.
Business
Griffin: peace dividend over, higher rates, inflation for longer.
Powell doesn't comment on outlook for rates, economy.
Fed's Goolsbee: Fed needs to monitor risks of rate overshooting.
Actor strike over as SAG-ASTRA, studios reach deal.
Crypto
FTX restart: Bullish, Figure Tech, Proof Group compete to buy exchange.
SEC Chair Gensler: reboot possible if βwithin the law.β
Jump Crypto investigated by SEC for role in Terra, Luna collapse.
Grayscale talking to SEC about spot Bitcoin ETF.
Emmer amendment could curb funding for SEC's enforcement actions.
U.S. politics
Haley, Ramaswamy trade barbs at 3rd GOP debate.
Trump won't attend 4th, final debate.
Senate votes 50-48 to overturn Biden's βBuy Americaβ for EVs, veto likely.
Glenn Youngkin, Virginia gov., won't run for president in 2024.
Ivanka Trump testifies at NY civil trial.
71% of CA adults think kids will be worse off financially.
World
South Korea, U.S. condemn North Korea for providing arms to Russia.
South Korea concerned about border, whether it could stop NK invasion.
Ukraine support losing steam since Israel-Hamas war.
Plan B Passport: learn how you can obtain one.*
*Sponsored.
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